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The Food Allergy Epidemic
Why Get Tested?
Do you have itching, sneezing, or sniffles? Are they coupled with symptoms you wouldn’t expect, such as stomach pain, diarrhea, or coughing? If so, these symptoms may be the result of an allergic reaction. Getting a correct diagnosis is the route to receiving appropriate help and optimal symptom relief. That is why it’s important to get tested for allergies to help your doctor make an appropriate allergy diagnosis.
What is component testing and why should I get it tested?
An estimated 32 million Americans (including children) – have food allergies and this number has been on the rise in the last two decades. Allergy component testing is a relatively new form of IgE blood testing that looks at the specific proteins or “components” of an allergen that cause a reaction, rather than the allergen as a whole. For example, 70% of children with egg allergies do not react to baked eggs while 75% of children with milk allergy do not react to baked milk. This may be because those children are specifically allergic to ovalbumin (in eggs), alpha-lactalbumin, or beta-lactoglobulin (in milk), which may become denatured when heated. For a patient suspected to have a peanut allergy, component testing looks at the IgE antibody levels for different peanut proteins. If the patient has high levels for the Ara h 2, studies show that this is a good indicator that the person is peanut-allergic. However, if the person instead has high levels of Ara h 8 or 9, then the symptoms are likely to be linked to a cross-reaction with pollen, a less severe condition known as oral allergy syndrome.
What are the benefits of Component Resolved:
Current tests define allergen-containing sources, not specific allergenic molecules:
Up to 50% of patients asymptomatic sensitization.
Up to 30% patients with FALSE positive results.
Distinguish between allergy due to cross-reactivity and primary allergy.
Improve the risk assessment using allergen components.
Improve management of allergic patients.
Ayass BioScience’s Allergy Panel Detecting Sensitizations of
Common Silver Birch
Mouse Urine Proteins
Common Wasp (Yellow Jacket)
The largest quality assessment program in the world
422 Allergens & 61 Components
Available Upon Request
Cat (rFel d 1) – Uteroglobin
Dog (rCan f 1) – Lipocalin
Dog (rCan f 2) – Lipocalin
Dog (rCan f 5) – Arginine esterase
Cow (nBos d 6) – Serum albumin
Cat (rFel d 2) – Serum albumin
Dog (nCan f 3) – Serum albumin
Horse (rEqu c 1) – Lipocalin
Cat (rFel d 4) – Lipocalin
Egg white (nGal d 2) – Ovalbumin
Egg white (nGal d 1) – Ovomucoid
Peach (rPru p 1) – PR-10 Protein
Peach (rPru p 3) – Lipid transfer protein (nsLTP)
Peach (rPru p 4) – Profilin
Shrimp (rPen a 1) – Tropomyosin
Peanut (rAra h 1) – Storage protein, 7S globulin
Peanut (rAra h 2) – Storage protein, 2S albumin, conglutin
Peanut (rAra h 3) – Storage protein, 11S globulin
Hazel nut (rCor a 8) – Lipid transfer protein (nsLTP)
Peanut (rAra h 9) – Lipid transfer protein (nsLTP)
Hazel nut (rCor a 1) – PR-10 Protein
Soy (nGly m 5) – Storage protein, vicilin
Soy (nGly m 6) – Storage protein, Glycinin
Soy (rGly m 4) – PR-10 Protein
Peanut (rAra h 8) – PR-10 Protein
Brazil nut (rBer e 1) – Storage protein, 2S albumin
Hazel nut (rCor a 14) – Storage protein, 2S albumin
Hazel nut (nCor a 9) – Storage protein, 11S globulin
Cashew nut (rAna o 3) – Storage protein, 2S albumin
Walnut (rJug r 1) – Storage protein, 2S albumin
Walnut (rJug r 3) – Lipid transfer protein (nsLTP)
Peanut (rAra h 6) – Storage protein, Conglutin
Cow’s milk (nBos d 4) – Alpha-lactalbumin
Cow’s milk (nBos d 5) – Beta-lactoglobulin
Cow’s milk (nBos d 8) – Casein
Bermuda grass (nCyn d 1) – Group 1 grass
Timothy grass (rPhl p 1) – Group 1 grass
Timothy grass (rPhl p 2) – Group 2 grass
Timothy grass (rPhl p 6) – Group 6 grass
Timothy grass (rPhl p 7) – Polcalcin
Timothy grass (rPhl p 12) – Profilin
Timothy grass (rPhl p 5b) – Group 5 grass
A. fumigatus (rAsp f 3) – Peroxisomal protein
A. fumigatus (Asp f 4) – unknown
A. alternata (rAlt a 1) – Acidic glycoprotein
House dust mite (rDer p 2) – NPC2 family
House dust mite (rDer p 10) – Tropomyosin
House dust mite (rDer p 1) – Group 1 Mites
Alpha-amylase (nAsp o 21) – n/a
Egg (nGal d 4) – Lysozyme
Papaya (nCar p 1) – Papain
Olive (nOle e 7) – Lipid transfer protein (nsLTP)
Olive (rOle e 9) – Glucanase
Birch (rBet v 1) – PR-10 Protein
Birch (rBet v 2) – Profilin
Birch (rBet v 4) – Profilin
Birch (rBet v 6) – Isoflavone reductases
Olive (rOle e 1) – Trypsin inhibitor
Ragweed (nAmb a 1) – Pectate lyase
Mugwort (nArt v 1) – Glycoprotein
Mugwort (nArt v 3) – Lipid transfer protein (nsLTP)
A number of studies have recently demonstrated that allergen component-resolved testing (CRT) may improve the specificity of testing for a variety of allergens. Allergen CRT can identify and quantify the levels of the parts or components of a suspected allergen that triggers allergic reactions.
Allergen CRT provides an accurate assessment for diagnosing allergies and assists with patient risk evaluation and identifying strategies for reducing and avoiding exposure to allergens, or with the selection of specific allergens for immunotherapy.
If you’d like to learn more about our exhaustive allergen testing 422 allergen and 61 components menu, please contact us – we have helpful information for you.
Source: Phadia. If you’d like to learn more about our exhaustive allergen testing 422 allergen & 61 components menu, we have helpful information for you. Please call today at 972-668-6005 or fill out our contact form on the bottom of this page. We will answer any question you might have.