How Will My Immune System Respond If Infected With COVID-19?
Flow Cytometry Assessing Immune Response to SARS-CoV-2
Flow Cytometry (FC) analysis is a useful tool for a variety of both clinical diagnostics and research applications and is used at Ayass BioScience laboratory for immunophenotyping and immune response profiling to SARS-CoV-2. We use FC’s ability to identify fluorescent-labeled cells based on fluorescence emission. Customized panels of markers are created to enable in-depth analysis of cell signaling and behavior in order to investigate how the immune system will react if introduced to SARS-CoV-2.
Immune System
The immune system is built to protect from harmful foreign substances (bacteria, viruses, and abnormal cells). The job of our immune system is to target and destroy such substances. However, SARS-CoV-2 can find ways to evade the immune response, allowing the virus to infuse in host cells.
Ayass BioScience’s research in this growing field focuses on finding ways to predict:
1. Potential Cytokine Storm on Patients Tested for SARS-CoV2
Cytokines are part of the body’s immune response to infection, but their sudden release in large quantities (Cytokine Storm) can cause multisystem organ failure and death.
2. Monitoring the COVID-19 Disease Progression
From incubation to recovery.
3. Better Prediction of Individual Outcome while Infected with COVID-19
Early prediction of aggressive COVID-19 progression and hospitalization.
4. To Better Select Therapeutic Measures
If you are being tested for COVID-19, would you bee interested in participating in the study?
Your participation is voluntary and is not part of your care or treatment. Your care won’t be affected whether you participate or not. This test requires a blood draw (two tubes of blood). The results will help us determine why some patients with COVID-19 recover fast, while others suffer from more severe symptoms. Our aim, once the test is developed, is to offer this as part of patient care for COVID-19 patients to help predict the disease outcome and provide them with better care.
Title of Study: Beckman Navios Flow Cytometric analysis for COVID 19 (SARS-CoV-2) Study
You are being asked to participate in a research study. No research activity is to be conducted until you have had an opportunity to review this consent form, ask any questions you may have, and sign this document. The purpose of this research study is to gather novel data regarding the immune response from patients known to be infected by SARS-CoV 2 virus and compare with unaffected individuals to better understand the mechanisms of viral response and to aid in the development of targeted therapy. Flow cytometric analysis is intended for in vitro diagnostic use in the identification of normal/abnormal blood cell populations. A given amount of peripheral blood sample (2 tubes, collected in K2EDTA and Heparin) drawn for the subject/patient continuation of care (including, but not limited to blood chemistries, white blood count) will be used for the flow cytometry instrument validation study. When the study sample is collected, it will be given a code number. No identifying information such as your name or birth date will be directly linked to your research sample. Although the results of this study may be published, no information that could identify you will be included. There is no compensation for participation in the validation study. Your participation in this study is complete once the blood has been collected. There are minimal risks, side effects or discomfort associated with peripheral blood draw (bleeding, rash, bruising, pain).
All tests and research are performed in Ayass BioScience, LLC. Ayass BioScience, LLC (DBA Ayass Lung Clinic, PLLC) is a CLIA certified laboratory. If you have any questions about Ayass BioScience, LLC COVID-19 Testing Call Our Hotline at 469-415-1600 or fill out our contact form on the bottom of this page. We will answer any question you might have.
