The protein encoded by this gene is a secreted cytokine that induces cardiac myocyte hypertrophy in vitro. It has been shown to bind and activate the ILST/gp130 receoptor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
- Cell surface receptor signaling pathway
- Cell-cell signaling
- Nervous system development
- Muscle organ development
- Positive regulation of cell proliferation
- Dilated cardiomyopathy
- Leukemia
- Hypertensive heart disease
- Neonatal stroke
- Motor neuron disease
CTF1 Localizations – Subcellular Localization Database
