Heart Failure
Non-Coding miRNAs in Cardiac Remodeling and Heart Failure
List of miRNAs that play an important role in the pathogenesis of heart failure by regulating the expression of genes that govern the process of cardiac remodeling.
Cardiac Hypertrophy
miRNAs and Their Targets in Cardiac Hypertrophy
miRNAs and their targets that are involved in gene switching, cellular hypertrophy, fibrosis, and electric remodeling during cardiac hypertrophy.
Myocardial Infarction
Cardiac Repair After Myocardial Infarction
A suggested hypothesis on the role of exosomes released from a damaged heart as a potential intercellular communicator.
Congenital Heart Disease / Cardiac Disease
Congenital Heart Disease / Cardiovascular Disease
Cardiomyopathy
Cardiomyopathy and the Role of miRNAs
List of miRNAs that play a keyrole in regulating the progression of cardiomyopathy.
Coronary Artery Disease
miRNAs and Coronary Artery Disease
Circulating miRNSs for biomarkers for Coronary Artery Disease.
Atherosclerosis
MicroRNAs and Atheroslcerosis
MiRNA expression is modulated by different stimuli involved in every stage of atherosclerosis, and conversely miRNAs modulates several pathways implicated in plaque development such as cholesterol metabolism.
Angiogenesis
Angiogenesis and the Role of miRNAs
miRNAs regulate angiogenesis by manipulating the expression of pro- and anti-angiogenic factors and endothelial cell functions.
Cardiac Ischemia
miRNAs and the Regulation of Cardiac Ischemia:
Dysregulation of miRNA expression contributes to ischemic heart disease.
Restenosis and Thrombosis after Vascular Injury
miRNAs for Restenosis and Thrombosis After Vascular Injury
miRNAs modulate vascular smooth muscle cell (VSMCs) proliferation, with their direct molecular targets.
Cardiac Regeneration
MicroRNAs and Cardiac Regeneration
Cardiac signaling and transcriptional pathways are intimately intertwined with microRNA molecules which act as modulators of cardiac development, function, and disease.
miRNA and HDL
miRNA Control of High-Density Lipoprotein Metabolism and Function
miRNA coordination of high-density lipoprotein (HDL) homeostasis. miRNAs have been shown to regulate genes involved in cholesterol efflux and HDL homeostasis in various tissues, including the liver, intestine, and macrophage.
miRNA and Cardiac Calcium Signaling
miRNA Regulation and Cardiac Calcium Signaling. Role in Cardiac Disease and Therapeutic Potential.
Given the critical role of Ca2+ handling and signaling proteins in the maintenance of cardiac function, the targeting of such proteins by miRNAs would be expected to have important consequences.
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