GENOMICS PROGRAMS:

Human Genotyping Arrays (iScan)

Methylation Array (iScan)

Animal Genotyping Arrays (iScan)

Plant Genotyping Arrays (iScan)

Next Generation Sequencing Targeted Panels (Miseq)

Aptamer Sequencing (Miseq)

Bioinformatics Services

Fast Turnaround Time

iScan

Human Genotyping Arrays (iScan)

At Ayass Bioscience, LLC we offer array-based genomic application services for research use. Tests are available for Human Genotyping, Plant Genotyping, Animal Genotyping and Methylation Array Analysis. We also have the capability to generate any custom panel for various applications. These tests are processed on the Illumina iScan System is a bench-top reader that utilizes Illumina’s BeadArray technology.

Identify mutations and variations in various types of human samples. The tests we offer support whole-genome, targeted genome and exome analysis for various applications using different sample types such as paraffin embedded tissues, fresh frozen tissues, whole blood, or cell lines. Click on the links below for detailed description of the services available.

HumanCytoSNP FFPE-12 BeadChip

Human Genotyping Array

HumanCytoSNP FFPE-12 BeadChip

This array is optimized for cytogenetic studies using formalin-fixed paraffin-embedded (FFPE) paired tumor and normal samples for characterizing more than 200,000 genomic markers.

 

HumanCytoSNP FFPE-12 BeadChip

HumanCytoSNP-12 BeadChip

Human Genotyping Array

HumanCytoSNP-12 BeadChip

This array enables analysis of genetic and structural variation in the human genome, including 300,000 SNPs, duplications, deletions, amplifications, loss of heterozygocity, and mosaicism. The test is designed to detect smaller regions than fluorescence in situ hybridization (FISH) comparative genomic hybridization (CGH).

HumanCytoSNP-12 BeadChip

Infinium Core-24 Kit

Human Genotyping Array

Infinium Core-24 Kit

This array enables economical large-scale human genotyping studies and includes 300,000 genome wide SNPs found across world populations.

Infinium Core-24 Kit

Infinium CoreExome-24 Kit

Human Genotyping Array

Infinium CoreExome-24 Kit

This array delivers large scale genotyping studies. It includes the Infinium Core-24 Kit plus 240,000 additional markers from Infinium Exome-24.

Infinium CoreExome-24 Kit

Infinium CytoSNP-850K v1.1 BeadChip

Human Genotyping Array

Infinium CytoSNP-850K v1.1 BeadChip

This array provides comprehensive overview of cytogenomic activity. It contains 850,000 SNPs that span the entire genome with enriched coverage for 3,626 genes relevant for cancer and congenital disorders.

Infinium CytoSNP-850K v1.1 BeadChip

Infinium Exome-24 Kit

Human Genotyping Array

Infinium Exome-24 Kit

This arrays delivers exonic variants from 12,000 exome and whole genome sequences  that represent diverse populations and a range of common conditions such as type II diabetes, cancer, psychiatric disorders among  others.

Infinium Exome-24 Kit

Infinium Global Screening Array-24 Kit

Human Genotyping Array

Infinium Global Screening Array-24 Kit

This array combines a highly optimized, universal genome-wide backbone; hand curated clinical research variants, and sample tracking content to create a highly economical array for population-scale genomics and screening. It can detect a total of 660,000 clinical markers that include SNPs, Indels, CNVs, structural, genic and intergenic.

Infinium Global Screening Array-24 Kit

Infinium ImmunoArray-24 v2 BeadChip Kit

Human Genotyping Array

Infinium ImmunoArray-24 v2 BeadChip Kit

The array is a genotyping array for detecting 250, 000 genetic variation in the immune system with focus on 17  major autoimmune disorders.

Infinium ImmunoArray-24 v2 BeadChip Kit

Infinium Multi-Ethnic AMR/AFR-8 Kit

Human Genotyping Array

Infinium Multi-Ethnic AMR/AFR-8 Kit

This array includes markers for the identification of genetic associations with focus on Hispanic and African American populations.

Infinium Multi-Ethnic AMR/AFR-8 Kit

Infinium Multi-Ethnic EUR/EAS/SAS-8 Kit

Human Genotyping Array

Infinium Multi-Ethnic EUR/EAS/SAS-8 Kit

This array includes markers for the identification of genetic associations with focus on European, East Asian, and South Asian populations.

Infinium Multi-Ethnic EUR/EAS/SAS-8 Kit

Infinium Multi-Ethnic Global-8 Kit

Human Genotyping Array

Infinium Multi-Ethnic Global-8 Kit

This array is designed to detect over 1.7 million markers for the identification of genetic association in diverse human populations.

Infinium Multi-Ethnic Global-8 Kit

Infinium Omni2.5-8 Kit

Human Genotyping Array

Infinium Omni2.5-8 Kit

This array contains about 2.5 million markers, for common and rare SNPs from the 1000 genome project.

Infinium Omni2.5-8 Kit

Infinium Omni2.5Exome-8 Kit

Human Genotyping Array

Infinium Omni2.5Exome-8 Kit

This Array combines the markers from  Infinium Omni2.5-8 Kit and Infinium Exome-24 Kit, to provide comprehensive coverage for common, rare and exonic SNPs from the 1000 genome project.

Infinium Omni2.5Exome-8 Kit

Infinium Omni5-4 Kit

Human Genotyping Array

Infinium Omni5-4 Kit

This array is optimized for whole-genome genotyping and CNV studies. It covers about 4.3 million variants.

Infinium Omni5-4 Kit

Infinium Omni5Exome-4 Kit

Human Genotyping Array

Infinium Omni5Exome-4 Kit

This array combines the 4.3 million whole-genome variants from the Infinium Omni5-4 Kit in addition to novel functional exonic variants.

Infinium Omni5Exome-4 Kit

Infinium OmniExpress-24 Kit

Human Genotyping Array

Infinium OmniExpress-24 Kit

This array is ideal for genome wide association studies and covers 710,000 markers.

Infinium OmniExpress-24 Kit

Infinium OmniExpressExome-8 Kit

Human Genotyping Array

Infinium OmniExpressExome-8 Kit

This array combines the power of genome wide association studies from the Infinium OmniExpress-24 Kit with the functional exonic content to drive the discovery of novel associations with traits and diseases.

Infinium OmniExpressExome-8 Kit

Infinium OmniZhongHua-8 Kit

Human Genotyping Array

Infinium OmniZhongHua-8 Kit

This array provides coverage for over 800,000 common, intermediate and rare markers found in the Chinese population for genome wide association studies.

Infinium OmniZhongHua-8 Kit

Infinium OncoArray-500K BeadChip

Human Genotyping Array

Infinium OncoArray-500K BeadChip

This array enables research into cancer predisposition and risk. It covers 500,000 markers.

Infinium OncoArray-500K BeadChip

Infinium PsychArray-24 Kit

Human Genotyping Array

Infinium PsychArray-24 Kit

This array analyzes over 500,000 markers to evaluate the risk and predisposition to psychiatric disorders. It includes Copy Number Variants (CNVs), Germline Variants, Insertions-Deletions (indels), Single Nucleotide Polymorphisms (SNPs), Structural Variants.

Infinium PsychArray-24 Kit

Infinium QC Array-24 Kit

Human Genotyping Array

Infinium QC Array-24 Kit

This array offers genotyping for quality control, tracking, and stratification applications including biobanking. It includes 15,949 markers for sex determination, ethnic ancestry, linkage analysis as well as ADME (absorption, distribution, metabolism, and excretion).

Infinium QC Array-24 Kit

Infinium QC Array-24 Kit

Human Genotyping Array

Infinium QC Array-24 Kit

This array offers genotyping for quality control, tracking, and stratification applications including biobanking. It includes 15,949 markers for sex determination, ethnic ancestry, linkage analysis as well as ADME (absorption, distribution, metabolism, and excretion).

Infinium QC Array-24 Kit

Methylation Array (iScan)

Infinium MethylationEPIC Kit

Methylation Array

Infinium MethylationEPIC Kit

This array offers analysis for over 850,000 methylation sites across the human genome at single nucleotide resolution. It is a great tool for epigenetic studies to analyze differences in gene expression. It provides extensive coverage of CpG islands, genes, and enhancers.

Infinium MethylationEPIC Kit

Animal Genotyping Arrays (iScan)

Identify mutations and variations for non-human organisms such as livestock and model organisms.

OvineSNP50 DNA Analysis Kit

Animal Genotyping Arrays

OvineSNP50 DNA Analysis Kit

This array features over 54,241 evenly spaced SNP probes for genome-wide association studies, genome-wide selection, and genetic merit determination in sheep.

OvineSNP50 DNA Analysis Kit

PorcineSNP60 DNA Analysis Kit v2

Animal Genotyping Arrays

PorcineSNP60 DNA Analysis Kit v2

This array features over 64,000 evenly distributed SNPs for genetic variation analysis of multiple porcine breeds.

PorcineSNP60 DNA Analysis Kit v2

BovineHD DNA Analysis Kit

Animal Genotyping Arrays

BovineHD DNA Analysis Kit

This array feature over 770,000 SNPs for genome side genotyping of any breed of beef or dairy cattle.

BovineHD DNA Analysis Kit

BovineLD Genotyping BeadChip

Animal Genotyping Arrays

BovineLD Genotyping BeadChip

This array offers genotyping for 7931 SNPs that offer valuable information for milk production, reproduction and health of bovine Extend genomic selection to the entire herd with scalable content at an economical price.

BovineLD Genotyping BeadChip

BovineSNP50 v3 DNA Analysis BeadChip

Animal Genotyping Arrays

BovineSNP50 v3 DNA Analysis BeadChip

This array identifies 53,714 markers for various applications including identification of quantitative trait loci, evaluation of genetic merit of individuals, and comparative genetic studies for genome characterization of major dairy and beef cattle breed types.

BovineSNP50 v3 DNA Analysis BeadChip

CanineHD Whole-Genome Genotyping BeadChip

Animal Genotyping Arrays

CanineHD Whole-Genome Genotyping BeadChip

This array feature 172,115 markers for genotyping of any domestic dog breed and offers SNP density for within-breed association and copy number variant (CNV) studies.

CanineHD Whole-Genome Genotyping BeadChip

Infinium ShrimpLD-24 BeadChip

Animal Genotyping Arrays

Infinium ShrimpLD-24 BeadChip

This array offers genotyping of 6,465 single nucleotide polymorphisms (SNPs)to advance aquaculture breeding programs of Pacific white shrimp.

Infinium ShrimpLD-24 BeadChip

Infinium XT

Animal Genotyping Arrays

Infinium XT

This array offers a comprehensive screening tool that can be used with any species by genotyping up to 50,000 single or multi-species Germline Variants, Insertions-Deletions (indels), and Single Nucleotide Polymorphisms (SNPs).

Infinium XT

Plant Genotyping Arrays (iScan)

Identify mutations and variations for plants for screening and discovery to aid in agricultural breeding decisions.

MaizeLD BeadChip Kit

Plant Genotyping Arrays

MaizeLD BeadChip Kit

This array covers 3,047 markers for essentially derived varieties (EDV) assessment and maize breeding applications. Samples used include the Plant Variety Protection Act panel.

MaizeLD BeadChip Kit

MaizeSNP50 DNA Analysis Kit

Plant Genotyping Arrays

MaizeSNP50 DNA Analysis Kit

This array offers genetic variation analysis across maize lines by analyzing over 50,000 validated markers derived from the B73 corn reference sequence.

MaizeSNP50 DNA Analysis Kit

Miseq

Next Generation Sequencing Targeted Panels (Miseq)

At Ayass Bioscience LLC we offer next generation sequencing services on the Miseq System from Illumina for research use. This system is ideal for cost effective targeted sequencing and fast turn-around time in a matter of days rather than weeks as compared to other sequencing methods.
Predesigned Kits are available through Illumina and we can custom make targeted panels for various study designs.

Identify mutations and variations in various types of human samples. The tests we offer support targeted exome genome and whole exome analysis for various applications using different sample types such as paraffin embedded tissues, fresh frozen tissues, whole blood, or cell lines. Click on the links below for detailed description of the services available.

Aptamer Sequencing

At Ayass Bioscience we offer next generation sequencing for aptamers. The conventional way of aptamer sequencing after the selection process relies on using cloning techniques followed by Sanger Sequencing. This approach gives information about the frequent clones. It is highly dependent on the success of the cloning technique and lead to loss of valuable target sequences. Next Generation Sequencing offers a lot of advantages by providing raw data sequencing and ranking them in terms of their abundance at very high resolution. Based on the number of reads, the best fit aptamer is selected for further downstream analysis.

AmpliSeq for Illumina BRCA Panel

Next Generation Sequencing Targeted Panels

AmpliSeq for Illumina BRCA Panel

Is a targeted sequencing panel investigating somatic and germline variants in BRCA1 and BRCA2.

AmpliSeq for Illumina BRCA Panel

AmpliSeq for Illumina Cancer Hotspot Panel v2

Next Generation Sequencing Targeted Panels

AmpliSeq for Illumina Cancer Hotspot Panel v2

Is a targeted sequencing panel investigating somatic mutations spanning across hotspot regions of 50 genes with known associations to cancer as reported in the Catalogue of Somatic Mutations in Cancer (COSMIC) database.

AmpliSeq for Illumina Cancer Hotspot Panel v2

AmpliSeq for Illumina Focus Panel

Next Generation Sequencing Targeted Panels

AmpliSeq for Illumina Focus Panel

Is a targeted sequencing panel that can use DNA or RNA for investigating 52 genes with known relevance to solid tumors.

AmpliSeq for Illumina Focus Panel

AmpliSeq for Illumina Custom DNA Panel

Next Generation Sequencing Targeted Panels

AmpliSeq for Illumina Custom DNA Panel

Is a targeted custom research panels optimized for sequencing specific targets or genomic content of interest.

AmpliSeq for Illumina Custom DNA Panel

TruSeq RNA Library Prep Kit v2

Next Generation Sequencing Targeted Panels

TruSeq RNA Library Prep Kit v2

This kit is designed for mRNA-focused sequencing from total RNA.

TruSeq RNA Library Prep Kit v2

Bioinformatics Services

Next Generation Sequencing Data Analysis

Our experienced bioinformatics specialists can help with any type of data analysis related to NGS. All these services can be customized depending on your requirements. The number of hours required for your project, specific objectives, and defined deliverables will be estimated during the initial consultation.

  • Sequence Quality control, e.g. adapter trimming
  • ChIP-Seq analysis
    • Read alignment: mapping sequencing reads to the reference genome
    • Peak calling: identify binding sites of the protein of interest
    • Data visualization
  • Microbial genomics if reference genome is available
  • Pathway enrichment analysis(GSEA)
    • A common approach to interpreting gene expression data is gene set enrichment analysis based on the functional annotation of the differentially expressed genes. We can help with gene set enrichment and pathway analysis using online open source and commercial tools listed below. We also offer Network analysis in complementary to pathway analysis.
    • DAVID
    • GSEA
    • Ingenuity (licence required)
    • Reactome
  • Comparative genomics
    • Aligning a pair of or multiple short sequences, molecular phylogenetics, sequence-based database searching, aligning a pair of or multiple genomes, multi-locus sequence typing and gene/protein clustering.
  • Analysis of epigenetic modifications, e.g. from methylation/chromatin data
  • Variant calling and variant annotation
  • RNA Seq analysis
  • Our bioinformatics team can help with transcriptome analysis (RNA-Seq projects), including expression analysis and isoform detection.
  • Cross-platform integration
    • Integration of SNP / polymorphism data
    • Integration with new genomics tools (epigenetics, chromatin structure)
    • Identification of relevant data in public repositories
    • Normalization of diverse datasets
    • Data formatting and updates
  • Computational assistance with experimental design
    • sequence retrieval
    •   primer design

Statistical Analysis Services

  • Logical checks of data
  • Tests of hypotheses
  • Development of statistical models
  • Testing of statistical assumptions for tests and models
  • Plots illustrating the results of analyses
  • Help with drafting abstracts, talks, posters, and manuscripts
  • Significance testing through randomization / numerical simulations
  • Statistical reporting

Designing Panel for Agena

  • Customized pharmacogenomics, cancer panels
  • Custom panel for small scale clinical use

If you have any questions about Research Programs at Ayass BioScience, LLC, please call today at 972-668-6005 or fill out our contact form on the bottom of this page. We will answer any question you might have.