Our ApoE QUAD Assay is a qualitative in vitro test that is designed to detect mutations in the ApoE gene.
This assay is performed using genomic DNA isolated from human peripheral whole blood specimens or buccal cells from mouthwash. It can detect and identify the following allelic variants in the ApoE gene: 388T>C and 526C>T and report the predicte isoforms on the high throughput system.
The predicted isoform call can be: [E3,E3], [E2,E3], [E2,E2], [E3,E4], [E4,E4], or [E2,E4].
These genetic variants affect the response to statins.