Anti-dsDNA (Anti–Double-Stranded DNA Antibodies)

This test measures antibodies that target the body’s own DNA, which are strongly associated with systemic lupus erythematosus (SLE).

• Diagnostic Specificity: Anti-dsDNA antibodies are considered a hallmark marker for lupus and are rarely seen in other conditions.
• Disease Activity Monitoring: Levels of these antibodies often rise and fall with lupus activity, especially in cases involving kidney inflammation (lupus nephritis).
• Clinical Guidance: Detecting Anti-dsDNA helps confirm diagnosis, monitor flares, and guide treatment decisions for patients with lupus.

Because of its close link to lupus and disease activity, the Anti-dsDNA test is an essential tool for both diagnosis and ongoing management.