This test identifies antibodies against thyroid peroxidase, an enzyme required for thyroid hormone synthesis.
Diagnostic Value: Elevated TPO antibodies are hallmark indicators of autoimmune thyroid diseases such as Hashimoto’s thyroiditis or Graves’ disease.
Clinical Significance: Persistent TPO antibodies signify ongoing thyroid inflammation, predicting progression to hypothyroidism even before symptoms arise.
Symptom Correlation: Patients may show gradual fatigue, dry skin, constipation, or swelling in the neck area due to chronic thyroid inflammation.
The TPO Antibody test provides critical insight into autoimmune thyroid activity and risk for long-term thyroid dysfunction.