Intrinsic Factor

This test detects antibodies against intrinsic factor, a protein required for vitamin B12 absorption in the stomach.

Diagnostic Value: Positive results indicate pernicious anemia, an autoimmune disorder that prevents B12 absorption.

Clinical Significance: Identifying intrinsic factor antibodies confirms the cause of vitamin B12 deficiency and directs appropriate treatment.

Symptom Correlation: Symptoms include weakness, numbness, and difficulty concentrating.

The Intrinsic Factor test helps pinpoint autoimmune causes of vitamin B12 deficiency.