This test measures Alpha-Fetoprotein (AFP), a protein produced by the fetal liver and yolk sac, which can reappear in certain cancers.
Diagnostic Value: Elevated AFP levels are commonly associated with liver cancer (hepatocellular carcinoma) and germ cell tumors.
Clinical Significance: AFP is used for diagnosis, prognosis, and treatment monitoring in patients with liver disease or malignancy risk factors.
Symptom Correlation: Increased AFP may coincide with abdominal pain, jaundice, or liver enlargement.
Because of its strong link to hepatic and germ cell tumors, AFP testing remains a cornerstone in liver cancer detection and management.