This test evaluates the body’s response to activated Protein C (APC). A resistance to APC — most commonly caused by the Factor V Leiden mutation — increases the risk of venous thrombosis.
Diagnostic Value: Detects activated protein C resistance, helping to identify Factor V Leiden carriers, the most common inherited cause of thrombophilia.
Clinical Significance: Useful for evaluating unexplained recurrent clots, family history of DVT, or clotting during pregnancy.
Symptom Correlation: Patients may have leg swelling, pain, or a history of clots in deep veins or lungs.
The APCR Screen F V test helps pinpoint genetic clotting risks and guide preventive management for thromboembolic disease