DHEA-S is a hormone produced primarily by the adrenal glands and serves as a precursor to both testosterone and estrogen. It plays a vital role in energy, immunity, and mood regulation.
Diagnostic Value: Measuring DHEA-S helps assess adrenal gland function and androgen production. Low levels may indicate adrenal insufficiency or aging-related decline, while high levels can signal polycystic ovary syndrome (PCOS) or adrenal tumors.
Clinical Importance: DHEA-S testing supports diagnosis of hormonal imbalances affecting fertility, libido, muscle tone, and mood. It also helps evaluate premature puberty in children and hirsutism (excess hair growth) in women.
Symptom Correlation: Abnormal levels may correspond with chronic fatigue, low sex drive, mood instability, or changes in body composition.
Because DHEA-S influences both male and female sex hormones, its measurement is an important part of understanding the body’s overall endocrine health.