This test measures lipase, a pancreatic enzyme responsible for breaking down dietary fats.
Diagnostic Value: Elevated lipase levels are highly specific for pancreatitis, pancreatic duct obstruction, or injury to pancreatic tissue. It typically remains elevated longer than amylase, providing a more stable diagnostic indicator.
Clinical Significance: Lipase testing helps differentiate pancreatic disease from other abdominal conditions and is critical for monitoring the severity and progression of inflammation.
Symptom Correlation: Common symptoms include sharp upper abdominal pain, nausea, vomiting, and tenderness that worsens after eating.
Because of its strong specificity for pancreatic injury, lipase testing is considered the most reliable biomarker for pancreatitis diagnosis and monitoring.