Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012]

  • Kidney development
  • Ion transport
  • Potassium ion transport
  • Heart development
  • Response to lipopolysaccharide
  • Cantu syndrome
  • Sudden infant death syndrome
  • Brugada syndrome
  • Brugada syndrome 1
  • Cantú syndrome and related disorders

KCNJ8 Localizations – Subcellular Localization Database

Gene Location