HEREDITARY CANCER

Our laboratory’s technology can accommodate small blood sample sizes or buccal cells from mouthwash, making it viable alternative to a trip to the phlebotomist and reducing the impact of blood-drawing on patients’ health.

HEREDITARY CANCER

Genetic Testing - Hereditary Cancer

GERMLINE MUTATION

The Hereditary Cancer panel targets 103 genes and 276 SNPs that have been previously linked to a predisposition to common and rare forms of cancer such as leukemia, ovarian cancer, breast cancer, prostate cancer, pancreatic  cancer, lung cancer, and skin cancer. This assay is performed using genomic DNA isolated from human peripheral whole blood specimens or buccal cells from mouthwash sample.

The test is intended to identify the variants that are associated with cancer. It is performed as a pre-symptomatic genetic test in order to determine whether persons with a family history of a cancer, but no current symptoms, has gene alterations associated with the disease. The test can also be used for post-symptomatic genetic testing to gain evidence to confirm variants of association to cancer.

HEREDITARY CANCER GENE LIST

HEREDITARY CANCER TESTING KIT

Genetic Testing - Hereditary Cancer

HEREDITARY CANCER TESTING PANELS

ABCB1,ACTRT3,AIMP2,AKT1,ALK,ALS2CR12,APC,AR,ARHGAP44,
ATF1,ATM,AXIN2,BAG6,BMPR1A,BRAF,BRCA1, BRCA2,BRIP1,
BUB1B,CASC17,CASC8,CCHCR1,CDH1,CDK10,CDKN1A,CDKN2A,
CHEK2,CHRNA3,CLPTM1L,COLCA1, CTD-2194D22.4,DBNDD1
DICER1,EGFR,EHBP1,ELAC2,ETS2,FGF10,FGFR4,FH,FLCN,HNF1B
HPDL,HYKK,IRF1,ITGA6, KLK3,KRAS,LAMA5,LMTK2,MAP2K7,
MAP4K2,MEN1,MIR5580,MITF,MLH3,MLPH,MPZ,MSH2,MSMB,
MSR1,MTAP, MUTYH,MX2,MXI1,NUDT11,PADI6,PALB2,PCAT2,
PDLIM5,PIGU,PMS2,POU5F1B,PTEN,RAD51,RAD54B,RAD54L,RB1,
RET,RFX6,RHPN2,RNA5SP299,RNASEL,RNU1-19P,RRAS2,RUNX1,
SDHB,SDHC,SDHD,SLC22A3,SMAD4,SMAD7,TERT,THADA,TP53,
TP63,TSC1,TUBB3,TYR,WEE1,XRCC1,XXYLT1,MT-ND3
RHPN2,CASC8,APC,RNA5SP299,ACTRT3,ATF1,RAD54B,AIMP2,
MLH3,AXIN2,TP53,HPDL,MT-ND3,COLCA1,MIR5580,LAMA5,
SMAD7,BUB1B,MUTYH,PMS2,MSH2,POU5F1B,BMPR1A,SLC22A3,
CDH1
RRAS2,PALB2,RAD54L,RAD51,BRIP1,CHEK2,MLH3,
BRCA1,BRCA2
TP63,EGFR,IRF1,RB1,BRAF,KRAS,XRCC1,CDKN1A,XXYLT1,
MAP2K7,BAG6,CLPTM1L,WEE1,ETS2,HYKK,CHRNA3

PCAT2,MSMB,ARHGAP44,PDLIM5,ITGA6,CTD-2194D22.4,
CCHCR1,AR,MXI1,CASC8,THADA,CASC17,FGF10,MLPH,KLK3,
RFX6,FGFR4,HNF1B,ELAC2,NUDT11,LMTK2,EHBP1,MSR1,
RNASEL,SLC22A3
MAP4K2,CHRNA3,PTEN,FH,CDKN2A,RB1,SDHB,TP53,RUNX1,
CDH1,ALS2CR12,FLCN,DICER1,TYR,MITF,TUBB3,BMPR1A,SDHC,
CDK10,SMAD4,MX2,DBNDD1,MTAP,RNU1-19P,PADI6,MPZ,RET,
MEN1,APC,PIGU

All tests are performed in Ayass BioScience, LLC. Ayass BioScience, LLC (DBA Ayass Lung Clinic, PLLC) is a CLIA certified laboratory. If you have any questions about Genetic Testing Next Generation Sequencing at Ayass BioScience, LLC, please call today at 972-668-6005 or fill out our contact form on the bottom of this page. We will answer any question you might have.