This gene encodes a subunit of a voltage-dependent calcium channel protein that is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome, an autoimmune disorder. Mutations in this gene are associated with Brugada syndrome. Alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Feb 2013]

  • Ion transport
  • Calcium ion transport
  • Chemical synaptic transmission
  • Neuromuscular junction development
  • Visual perception

  • Brugada syndrome 4
  • Lambert-eaton myasthenic syndrome
  • Brugada syndrome
  • Early repolarization associated with ventricular fibrillation
  • Short qt syndrome

CACNB2 (calcium voltage-gated channel auxiliary subunit beta 2) – BioGPS

Interacting Proteins for CACNB2 Gene – String

CACNB2 localizations – Subcellular Localization Database

Emw. Structure of the CACNB2 protein. Based on PyMOL rendering of PDB 1t0h.

Gene Location