This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008]

  • Skeletal system development
  • Angiogenesis
  • Blood vessel development
  • Renal system process involved in regulation of systemic arterial blood pressure
  • Regulation of systemic arterial blood pressure
  • Atrial fibrillation, familial, 11
  • Atrial standstill 1
  • Familial atrial fibrillation
  • 1q21.1 recurrent microdeletion
  • Atrial fibrillation

Gene Location