The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
- Regulation of heart rate
- Carbohydrate metabolic process
- Glycerol-3-phosphate metabolic process
- NOT NADH oxidation
- Phosphatidic acid biosynthetic process
- Brugada syndrome 2
- Brugada syndrome
- Sudden infant death syndrome
- Right bundle branch block
- Long qt syndrome
GPD1L Localizations – Subcellular Localization Database
