![SALL4-a](https://ayassbioscience.com/wp-content/uploads/2020/12/SALL4-a.png)
This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
- Negative regulation of transcription by RNA polymerase II
- In utero embryonic development
- Inner cell mass cell proliferation
- Neural tube closure
- Ventricular septum development
- Duane-radial ray syndrome
- Ivic syndrome
- Okihiro syndrome due to a point mutation
- Duane retraction syndrome
- Okihiro syndrome due to 20q13 microdeletion
Gene Location
![SALL4-c](https://ayassbioscience.com/wp-content/uploads/2020/12/SALL4-c.png)